RNA Details
Disease Name
heart failure
Tissue
heart
RNA Symbol
mir-208a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; Masson's trichrome staining etc.
Target
ENDOGLIN
Pathway
NA
PubMed ID
Title
MicroRNA-208a Increases Myocardial Fibrosis via Endoglin in Volume Overloading Heart
Year
2014
Function
miR-208a increased endoglin expression to induce myocardial fibrosis in volume overloaded heart failure. Treatment with atorvastatin can attenuate the myocardial fibrosis induced by volume overload through inhibition of endoglin expression.